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Anti-CD4, Type: Monoclonal, Host: Rat, Clone#: GK1.5
Catalog #: AI001S

Anti-CD4, Type: Monoclonal, Host: Rat, Clone#: GK1.5, Immunogen: Mouse CD4, Size: 100ug


Product Anti-CD4 antibody (GK1.5)
Cat #  AI001S Qty/Pk: 100µg   Made in U.S.A
Description CD4 is a member of the immunoglobulin superfamily which is expressed on the surface of helper T cells, macrophages, monocytes, regulatory T cells (Tregs), and dendritic cells. CD4 (also designated T4 and Leu 3), is a membrane glycoprotein that contains four extracellular immunoglobin-like domains and is required for efficient signal transduction. The TCR in association with CD4 can bind class II MHC molecules presented by the antigen-presenting cells. The CD4 protein functions by increasing the avidity of the interaction between the TCR and an antigen-class II MHC complex. CD4 is known to function as a receptor for HIV infection. The GK1.5 monoclonal antibody reacts with the mouse CD4 cell surface receptor.
This antibody was created by immunization of rat with mouse immunogen. The resultant hybridomas were selected with the immunogen and the antibody was purified with protein G. 
Host Rat
Immunogen Cloned mouse cytotoxic T lymphocyte (CTL) line V4
Clone Monoclonal (GK1.5)
Isotype IgG2bk
Conjugation/Label Unconjugated
Specificity CD4/L3T4, T4/Leu-3, Mr 52 kDa.
Reactivity Mouse
 Purity Greater than 95% as determined by SDS-PAGE
Concentration 1.0 mg/ml
Physical appearance Colorless clear solution
Storage condition PBS with 10% glycerol and 0.01% sodium Azide.
Stability Store at 4oC for one month. Aliquot small amount for storage to avoid freezing and thawing cycles and store at -20oC for 12 months.
Application ELISA, WB (1/5,000 dilution), IHC and IP etc.
Regulatory statement For research use only. Not for use as drugs or in diagnostics.

This product was added to our catalog on Tuesday 14 October, 2014.
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